23 June 2017

Cardiopulmonary exercise factors predict survival in patients with advanced interstitial lung disease referred for lung transplantation

Posted in Scientific News, Research News, Clinical CPET

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The Respiratory Medicine Journal presents a new study demonstrating the prognostic value of CPET test parameters as pre-assessment tool for lung transplant ILD patients.

The purpose of this work was to determine if parameters assessed during Cardiopulmonary Exercise Testing (CPET) while using supplemental oxygen can independently predict one-year transplant- free survival in patients with Interstitial Lung Disease (ILD) referred for lung transplant evaluation.

The study comprised a chart review of patients with ILD who completed CPET with 30% FiO2 and gathered spirometry, pulmonary hemodynamic, six-minute walk, and CPET data. The primary end-point was death or lung transplantation within one-year of CPET.

The findings of this research "demonstrate the potential of added prognostic value in measuring peak workload and nadir SpO2 by CPET to identify patients who have an increased likelihood of clinical deterioration and death".

The article details are the following:

- Title: "Cardiopulmonary exercise factors predict survival in patients with advanced interstitial lung disease referred for lung transplantation"
- Authors: Layton AM, Armstrong HF, Kim HP, Meza KS, D'Ovidio F, Arcasoy SM
- Published in
: Respir Med. 2017 May;126:59-67

The study can be purchased at the following link: click here


Founded in 1980, COSMED is a privately owned company manufacturing Cardio Pulmonary and Metabolic Diagnostic Equipment. COSMED products include a full range of Spirometers, Pulmonary Function, Body Composition, Nutritional Assessment and Cardio Pulmonary Exercise systems, including Electrocardiographs, Ergometers and Assessment Software. COSMED solutions are aimed for either professional or medical use for many different applications like: Hospital, Clinics, Primary Care, University & Education in Human Physiology, Clinical Nutrition, Commercial Weight Management, Human Performance Centers, Sport Institutions and Health Club Industry. COSMED Headquarters are located in the province of Rome, Italy. COSMED has subsidiaries in the USA, China and Germany, and distributes its products internationally through a constantly growing distributor network covering more than 70 countries.